Well, symptoms I have discovered while worrying about plastics in the Ocean that Ethinylestriadiol in the water systems due to the hardiness of it in Birth Control pills threatens the purity of the water.
My advisors say a new paradigm needs to be applied to water treatment plant operations on this issue, ampoule as well as the other drugs and their ingredients excreted.
The effects of these things in the water are seen in hermaphroditic lizards, as well as being implicated in earlier maturation of girls, and changes in the physiology of young boys.
It would seem that there is a freshwater inland and close to shore problem, and an out at sea problem.